Toxoplasma gondii es un protozoo del Subphylum Apicomplexa y de la sub clase Coccidia que presenta un ciclo de multiplicación sexuada, en el intestino del gato (huésped completo) y otro de reproducción asexuada, en los tejido de una gran variedad de aves y mamíferos, incluyendo al hombre (huéspedes incompletos). Este parasito produce patología por su obligado carácter parasitario intracelular, puede infectar a cualquier tipo de célula nucledada del hombre o animal.
Características:- Es un protozoo curvo, donde su tamaño promedia las 4 a 6 micras de longitud y 2 a 3 de ancho, se caracterizan por tener un complejo apical que les permite perforar los tejidos (conoide), poseen un solo núcleo y no presentan cilios ni flagelos, por lo que se desplazan a través de ondulaciones o deslizamiento de su cuerpo celular.
Este protozoario coccidio se puede observar en tres formas:
Trofozoito-taquizoito: perteneciente a la forma asexual invasiva y se asocian con la enfermedad aguda. Son formas motiles capaces de formar quistes en tejidos. Se encuentran en vacuolas parasitóforas dentro de las células infectadas. Tienen forma de media luna, con 2-4 um de ancho y 4-8 um de largo. Se multiplican cada 4-6 horas.
Quiste con bradizoitos: se asocia con la enfermedad crónica y latente. Forma de replicación lenta. Esta tiene bradizoitos que se presentan en conglomerados microscópicos envueltos por una pared llamada quiste (los quistes son mas frecuentes en cerebro, musculo y corazón) y es capaz de persistir en los tejidos. Miden aproximadamente 10-100 um.
- Oosquistes: son el producto del ciclo sexual en el intestino del gato y son eliminados por las heces. Tienen forma oval y pueden contener hasta 8 esporozoitos en su interior (es la fase esporulada), en este estado puede sobrevivir por largos periodos de tiempo fuera del hospedero y posee una gran resistencia al medio ambiente . Miden 10 – 12 um de diámetro.
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